Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006597)
Formula
SVG example
Aliphatic hydroxylation
Reactant Dabrafenib mesylate Product Hydroxy-dabrafenib
Reactant Info Product Info
Metabolic Type Oxidation - Aliphatic hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006598 Hydroxy-dabrafenib Carboxy-dabrafenib Oxidation - Oxidationn Dabrafenib mesylate [1]
References
1 Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.