Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007045)
Formula	UGT1A8 Glucuronidation
	Reactant	Hydroxyestradiol	Product	4-hydroxyestradiol 4-glucuronide
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	UDP-glucuronosyltransferase 1A8 (UGT1A8)				DME Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR007046	Hydroxyestradiol	4-hydroxyestradiol 3-glucuronide	Conjugation - Glucuronidation	Hydroxyestradiol	[1]

References
1	Structural and functional studies of UDP-glucuronosyltransferases. Drug Metab Rev. 1999 Nov;31(4):817-99.

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