Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007087)
Formula
CYP2C9 ...
SVG example
Hydrolyzationn
Reactant Desogestrel Product 3alpha-OH-desogestrel
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007101 Desogestrel 13-Ethyl OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007092 Desogestrel 15alpha-OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007100 Desogestrel 16-OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007095 Desogestrel 2-OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007090 Desogestrel 3beta-OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007096 Desogestrel 5alpha-Hydrodesogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007097 Desogestrel 5beta-Hydrodesogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007098 Desogestrel 6alpha-OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007099 Desogestrel 6beta-OH-desogestrel Oxidation - Hydrolyzationn Desogestrel [1]
MR007094 Desogestrel Desogestrel sulfate Conjugation - Sulfation Desogestrel [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007089 3alpha-OH-desogestrel 3-Ketodesogestrel Oxidation - Oxidationn Desogestrel [1]
MR007088 3alpha-OH-desogestrel Desogestrel conjugates Conjugation - Glucuronidation Desogestrel [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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