| General Information of This Metabolic Reaction (MR) (ID:
MR007242) |
| Formula |
Reactant |
ABT-751 |
Product |
ABT-751 glucuronide |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
UDP-glucuronosyltransferase 1A1 (UGT1A1)
|
DME Info
|
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UDP-glucuronosyltransferase 1A4 (UGT1A4)
|
DME Info
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UDP-glucuronosyltransferase 1A8 (UGT1A8)
|
DME Info
|
|
UDP-glucuronosyltransferase 2B7 (UGT2B7)
|
DME Info
|
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| Other MR(s) Related to The Reactant of This MR |
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Other MR(s) That Metabolize The Reactant of This MR
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| References |
| 1 |
Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751. Pharmacogenet Genomics. 2013 Jul;23(7):374-81.
|
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