Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007347)
Formula
CYP
SVG example
3'-hydroxylation
Reactant Genistein Product 3'-hydroxygenistein
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 (CYP) DME Info
Metabolic Type Oxidation - 3'-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007332 BRN-0064479 Genistein Unclear BRN-0064479 [1]
MR008592 Puerarin Puerarin metabolite M21 Oxidation - Hydroxylation Puerarin [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007333 Genistein 6'-hydroxy-O-desmethylangolensin Unclear BRN-0064479 [1]
MR007340 Genistein Genistein-4'-glucuronide Unclear BRN-0064479 [3]
MR007345 Genistein Genistein-4'-sulfate Unclear BRN-0064479 [3]
MR007337 Genistein Genistein-7-glucuronide Unclear BRN-0064479 [3]
MR007343 Genistein Genistein-7-sulfate Unclear BRN-0064479 [3]
MR008593 Puerarin metabolite M21 Puerarin metabolite M55 Unclear - Unclear Puerarin [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007318 BIO-300 3'-hydroxygenistein Oxidation - 3'-hydroxylation BIO-300 [3]
References
1 Comparative metabolism of genistin by human and rat gut microflora: detection and identification of the end-products of metabolism
2 Rapid profiling and identification of puerarin metabolites in rat urine and plasma after oral administration by UHPLC-LTQ-Orbitrap mass spectrometer
3 Genistein: Dual Role in Women's Health

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