Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007441)
Formula Reactant Sennidins Product Rheinanthrone
Reactant Info Product Info
Metabolic Enzyme Beta-glucosidase (bglA) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007440 Sennidin-8-monoglucoside Sennidins Unclear DB-041901 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007442 Rheinanthrone Rhein Oxidation - Oxidationn DB-041901 [2]
References
1 Metabolism of sennosides by human intestinal bacteria
2 Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract

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