Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007688)
Formula
SVG example
S-oxidation
Reactant 6bate-OH-7alpha-methylsulfinylSpironolactone Product 6bate-OH-7alpha-methylsulfonylSpirolactone
Reactant Info Product Info
Metabolic Type Oxidation - S-oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007687 6bate-OH-7alpha-thiomethylSpirolactone 6bate-OH-7alpha-methylsulfinylSpironolactone Conjugation - S-methylation Spironolactone [1]
MR007691 7alpha-methylsulfinylSpirolactone 6bate-OH-7alpha-methylsulfinylSpironolactone Oxidation - Hydroxylation Spironolactone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007689 6bate-OH-7alpha-methylsulfonylSpirolactone Spironolactone metabolite XIV Unclear - Unclear Spironolactone [2]
References
1 The metabolism and biopharmaceutics of spironolactone in man
2 Spironolactone: disposition, metabolism, pharmacodynamics, and bioavailability

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