Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007867)
Formula Reactant Pimavanserin metabolite M8 Product Pimavanserin metabolite M12
Reactant Info Product Info
Metabolic Type Multi-steps Reaction - Hydroxylation; demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007865 Pimavanserin Pimavanserin metabolite M8 Oxidation - Hydroxylation Pimavanserin [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007868 Pimavanserin metabolite M8 Pimavanserin metabolite M10 Multi-steps Reaction - Hydroxylation; dehydrogenated Pimavanserin [1]
MR007866 Pimavanserin metabolite M8 Pimavanserin metabolite M13 Unclear - Unclear Pimavanserin [1]
References
1 Investigation of metabolic profile of pimavanserin in rats by ultrahigh-performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry

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