| General Information of This Metabolic Reaction (MR) (ID:
MR007967) |
| Formula |
|
| Reactant |
Tiaprofenic acid |
Product |
Reduced tiaprofenic acid |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
NADPH-dependent carbonyl reductase 1 (CBR1)
|
DME Info
|
|
Aldo-keto reductase 1A1 (AKR1A1)
|
DME Info
|
|
Small intestine reductase (AKR1B10)
|
DME Info
|
|
Aldo-keto reductase 1C4 (AKR1C4)
|
DME Info
|
|
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1)
|
DME Info
|
|
Metabolic Type
|
Reduction
-
Reduction
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
|
|
|
| References |
| 1 |
Reductive metabolism of tiaprofenic acid by the human liver and recombinant carbonyl reducing enzymes
|
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