Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008172)
Formula	Unclear
	Reactant	Tucatinib metabolite M25	Product	Tucatinib metabolite M19
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008171	Tucatinib	Tucatinib metabolite M25	Oxidation - Oxazoline ring oxidation	Tucatinib	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008170	Tucatinib metabolite M1	Tucatinib metabolite M19	Unclear - Unclear	Tucatinib	[1]

References
1	Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl

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