Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008281)
Formula
SVG example
Hydroxylation
Reactant VATALANIB Product VATALANIB metabolite M38
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008277 VATALANIB VATALANIB metabolite M1 Unclear - Unclear VATALANIB [1]
MR008278 VATALANIB VATALANIB metabolite M15 Conjugation - Glucuronidation VATALANIB [2]
MR008279 VATALANIB VATALANIB metabolite M17 Unclear - Unclear VATALANIB [2]
MR008280 VATALANIB VATALANIB metabolite M24 Oxidation - Hydroxylation VATALANIB [2]
MR008282 VATALANIB VATALANIB metabolite M26 Oxidation - Hydroxylation VATALANIB [2]
References
1 Machine learning-driven identification of drugs inhibiting cytochrome P450 2C9
2 Metabolism and disposition of vatalanib (PTK787/ZK-222584) in cancer patients

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