Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR008445)
Formula	MAOB ... Unclear
	Reactant	KW-2449		Product	KW-2449 metabolite M1
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Monoamine oxidase type B (MAO-B)					DME Info
Metabolic Enzyme	Aldehyde oxidase (AOX1)					DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008446	KW-2449	KW-2449 metabolite M2	Unclear - Unclear	KW-2449	[1]
MR008447	KW-2449	KW-2449 metabolite M3	Unclear - Unclear	KW-2449	[1]
MR008448	KW-2449	KW-2449 metabolite M4	Unclear - Unclear	KW-2449	[1]

References
1	Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in human

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