Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008497)
Formula Reactant Ibrolipim Product Ibrolipim metabolite M-1
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008501 Ibrolipim Ibrolipim metabolite M-2 Unclear - Unclear Ibrolipim [1], [2]
MR008500 Ibrolipim Ibrolipim metabolite M-3 Unclear - Unclear Ibrolipim [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008498 Ibrolipim metabolite M-1 Ibrolipim metabolite M-4 Oxidation - Hydroxylation Ibrolipim [1]
References
1 Pharmacokinetics and metabolism of NO-1886, a lipoprotein lipase-promoting agent, in cynomolgus monkey
2 Phosphonate O-deethylation of [4-(4-bromo-2-cyano-phenylcarbamoyl) benzyl]-phosphonic acid diethyl ester, a lipoprotein lipase-promoting agent, catalyzed by cytochrome P450 2C8 and 3A4 in human liver microsomes

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