Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008718)
Formula
SVG example
Hydrolysis
Reactant Temocapril Product Diacid metabolite
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 1 (CES1) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008717 Temocapril hydrochloride Diacid metabolite Hydrolysis - Hydrolysis Temocapril hydrochloride [1], [2]
References
1 Study on pharmacokinetics of a new biliary excreted oral angiotensin converting enzyme inhibitor, temocapril (CS-622) in humans
2 Influence of ionization state on the activation of temocapril by hCES1: a molecular-dynamics study

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