Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008878)
Formula	Unclear
	Reactant	Lasofoxifene	Product	Lasofoxifene metabolite M13
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008875	Lasofoxifene	5-hydroxy-lasofoxifene (5-OHLAS)	Oxidation - 5-hydroxylation	Lasofoxifene	[1]
MR008874	Lasofoxifene	7-hydroxy-lasofoxifene (7-OHLAS)	Oxidation - 7-hydroxylation	Lasofoxifene	[1]
MR008877	Lasofoxifene	Lasofoxifene metabolite M11	Conjugation - Sulfate conjugation	Lasofoxifene	[2]
MR008872	Lasofoxifene	Lasofoxifene metabolite M15	Unclear - Unclear	Lasofoxifene	[2]
MR008876	Lasofoxifene	Lasofoxifene metabolite M7	Unclear - Unclear	Lasofoxifene	[2]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR008873	Lasofoxifene metabolite M15	Lasofoxifene metabolite M13	Unclear - Unclear	Lasofoxifene	[2]

References
1	Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects
2	Metabolism, distribution, and excretion of a next generation selective estrogen receptor modulator, lasofoxifene, in rats and monkeys

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