Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008931)
Formula Reactant DEP-isocyanate Product Fotemustine metabolite II
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008930 Fotemustine DEP-isocyanate Unclear - Unclear Fotemustine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008932 Fotemustine metabolite II DEP-SG Unclear - Unclear Fotemustine [1]
MR008933 Fotemustine metabolite II Fotemustine metabolite VI Unclear - Unclear Fotemustine [2]
References
1 Molecular mechanisms of toxic effects of fotemustine in rat hepatocytes and subcellular rat liver fractions
2 Chemical and glutathione conjugation-related degradation of fotemustine: formation and characterization of a glutathione conjugate of diethyl (1-isocyanatoethyl)phosphonate, a reactive metabolite of fotemustine

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