Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008971)
Formula Reactant Sarpogrelate metabolite M-1 Product M-1 N-glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A4 (UGT1A4) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008970 Sarpogrelate Sarpogrelate metabolite M-1 Conjugation - Glucuronidation Sarpogrelate [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008972 Sarpogrelate metabolite M-1 SMG1 Conjugation - Glucuronidation Sarpogrelate [1]
MR008973 Sarpogrelate metabolite M-1 SMG3 Conjugation - Glucuronidation Sarpogrelate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008969 Sarpogrelate N-glucuronide M-1 N-glucuronide Conjugation - Glucuronidation Sarpogrelate [1]
References
1 Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4

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