Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008983)
Formula
SVG example
Unclear
Reactant Pheniramine Product N-oxide
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008981 Pheniramine N-desmethylpheniramine Oxidation - N-demethylation Pheniramine [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008979 Brompheniramine N-oxide Unclear - Unclear Brompheniramine [3]
References
1 Urinary excretion of pheniramine and its N-demthylated metabolites in man--comparison with chlorpheniramine and brompheniramine data
2 Pharmacokinetics of pheniramine (Avil) and metabolites in healthy subjects after oral and intravenous administration
3 Fungal transformations of antihistamines: metabolism of brompheniramine, chlorpheniramine, and pheniramine to N-oxide and N-demethylated metabolites by the fungus Cunninghamella elegans

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