Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009510)
Formula
SVG example
N-dealkylation
Reactant Rasagiline mesylate Product 1-aminoindan
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009512 Rasagiline mesylate 3-hydroxy-N-propargyl-1 aminoindan Oxidation - Hydroxylation Rasagiline mesylate [1]
MR009513 Rasagiline mesylate Unclear Unclear - Unclear Rasagiline mesylate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009511 1-aminoindan 3-hydroxy-1-aminoindan Oxidation - Hydroxylation Rasagiline mesylate [1]
References
1 Simultaneous bioanalysis of rasagiline and its major metabolites in human plasma by LC-MS/MS: Application to a clinical pharmacokinetic study
2 Pharmacokinetic interaction study between flavanones (hesperetin, naringenin) and rasagiline mesylate in wistar rats

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