Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009662)
Formula
SVG example
N-deethylation
Reactant N-desethyl blonanserin Product Blonanserin M3
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Metabolic Type Oxidation - N-deethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009661 AD-5423 N-desethyl blonanserin Oxidation - N-deethylation AD-5423 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009663 Blonanserin M3 Blonanserin M4 Oxidation - Oxidative deamination AD-5423 [2]
References
1 Simultaneous determination of blonanserin and its metabolite in human plasma and urine by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study
2 Simultaneous determination of blonanserin and its four metabolites in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry

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