General Information of This Metabolic Reaction (MR) (ID:
MR009806) |
Formula |
|
Reactant |
GDC-0623 |
Product |
GDC-0623 M14 |
Reactant Info
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Product Info
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Metabolic Enzyme
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME Info
|
Cytochrome P450 2C9 (CYP2C9)
|
DME Info
|
Metabolic Type
|
Unclear
-
Unclear
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Other MR(s) Related to The Reactant of This MR |
Other MR(s) That Metabolize The Reactant of This MR
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References |
1 |
Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450-Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
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