Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009974)
Formula Reactant 6-thioxanthosine monophosphate Product 6-thioguanine nucleotides
Reactant Info Product Info
Metabolic Enzyme Glutamine amidotransferase (GMPS) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009973 6-thioinosine monophosphate 6-thioxanthosine monophosphate Unclear - Unclear Mercaptopurine [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009900 6-thioxanthosine-monophosphate 6-thioguanine nucleotides Unclear - Unclear Azathioprine [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009975 6-thioguanine nucleotides 6-thioguanine monophosphate Unclear - Unclear Mercaptopurine [1], [2]
References
1 Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease
2 6-Mercaptopurine metabolism in Crohn's disease: correlation with efficacy and toxicity
3 Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease

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