Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010451)
Formula	EPHX1 Unclear
	Reactant	PR-025	Product	Oprozomib Metabolite M3
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Epoxide hydrolase 1 (EPHX1)				DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR010450	Oprozomib	PR-025	Unclear - Unclear	Oprozomib	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR010449	PR-176	Oprozomib Metabolite M3	Other reaction - Cleavage	Oprozomib	[1]

References
1	In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s

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