Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010599)
Formula
SVG example
Unclear
Reactant N-0923 Metabolite M4 Product N-0923 Metabolite M6c
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010597 N-0923 N-0923 Metabolite M4 Unclear - Unclear N-0923 [1]
MR009258 Neupro N-desthienylethyl-rotigotine Unclear - Unclear Neupro [2]
MR009597 Rotigotine N-desthienylethyl-rotigotine Unclear - Unclear Rotigotine [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010598 N-0923 Metabolite M4 N-0923 Metabolite M14 Unclear - Unclear N-0923 [1]
MR010600 N-0923 Metabolite M4 N-0923 Metabolite M5 Unclear - Unclear N-0923 [1]
MR009599 N-desthienylethyl-rotigotine N-desthienylethyl-rotigotine Glucuronide Conjugation - Glucuronidation Rotigotine [2]
MR009598 N-desthienylethyl-rotigotine N-desthienylethyl-rotigotine Sulfate Oxidation - Sulfonation Rotigotine [2]
MR009259 N-desthienylethyl-rotigotine Neupro Metabolite M3 Unclear - Unclear Neupro [2]
MR009260 N-desthienylethyl-rotigotine Neupro Metabolite M6 Unclear - Unclear Neupro [2]
References
1 Determination of the dopamine D2 agonist N-0923 and its major metabolites in perfused rat livers by HPLC-UV-atmospheric pressure ionization mass spectrometry
2 Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery

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