General Information of This Metabolic Reaction (MR) (ID: MR011488)
Formula
SVG example
N-dealkylation
Reactant Naldemedine carboxylic acid Product MS416
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011485 S-297995 Naldemedine carboxylic acid Hydrolysis - Hydrolysis S-297995 [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011486 Naldemedine carboxylic acid MS486 Oxidation - Oxidation S-297995 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011490 Nor-naldemedine MS416 Multi-steps Reaction - Reduction; Hydrolysis S-297995 [1]
References
1 Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects

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