Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011492)
Formula	Oxidation,Glycine conjugation
	Reactant	Benzamidine	Product	MS179
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Multi-steps Reaction - Oxidation,Glycine conjugation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR011491	S-297995	Benzamidine	Multi-steps Reaction - Reduction; Hydrolysis	S-297995	[1]

Other MR(s) Related to The Product of This MR

Other MR(s) That Produce The Product of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR009757	GDC-0152 M28	GDC-0152 M24	Unclear - Unclear	GDC-0152	[2]

References
1	Absorption, distribution, metabolism, and excretion of radiolabeled naldemedine in healthy subjects
2	Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole

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