Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011532)
Formula Reactant GSK2269557 Product GSK2269557 Metabolite M7
Reactant Info Product Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011530 GSK2269557 GSK2269557 Metabolite M1 Oxidation - N-dealkylation GSK2269557 [1]
MR011536 GSK2269557 GSK2269557 Metabolite M14 Conjugation - Glucuronide conjugation GSK2269557 [1]
MR011535 GSK2269557 GSK2269557 Metabolite M15 Oxidation - Oxidation GSK2269557 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011534 GSK2269557 Metabolite M7 GSK2269557 Metabolite M3 Conjugation - Glucuronide conjugation GSK2269557 [1]
MR011533 GSK2269557 Metabolite M7 GSK2269557 Metabolite M6 Multi-steps Reaction - Oxidation; Sulfate conjugation GSK2269557 [1]
References
1 Pharmacokinetics and metabolism of ulixertinib in rat by liquid chromatography combined with electrospray ionization tandem mass spectrometry

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