Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011691)
Formula
SVG example
Hydrolysis
Reactant CO-1686 Metabolite M544 Product CO-1686 Metabolite M502
Reactant Info Product Info
Metabolic Enzyme Carboxylesterase 2 (CES2) DME Info
Metabolic Type Hydrolysis - Hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011690 CO-1686 Metabolite M502 CO-1686 Metabolite M544 Conjugation - N-acetylation CO-1686 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011687 CO-1686 CO-1686 Metabolite M502 Unclear - Unclear CO-1686 [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011688 CO-1686 Metabolite M502 CO-1686 Metabolite M460 Hydrolysis - Hydrolysis CO-1686 [1]
MR011690 CO-1686 Metabolite M502 CO-1686 Metabolite M544 Conjugation - N-acetylation CO-1686 [1]
References
1 Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.