Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011748)
Formula
UGT
SVG example
Unclear
Reactant 1-Naphthol Product INX-09056
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronyltransferase (UGT) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011747 INX-189 1-Naphthol Unclear - Unclear INX-189 [1]
MR002194 Propranolol hydrochloride 1-Naphthol Unclear Propranolol hydrochloride [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011749 1-Naphthol INX-09077 Unclear - Unclear INX-189 [1]
References
1 In Vitro Metabolite Formation in Human Hepatocytes and Cardiomyocytes and Metabolism and Tissue Distribution in Monkeys of the 2'-C-Methylguanosine Prodrug BMS-986094 : Potential Role in Clinical Cardiovascular Toxicity
2 Propranolol metabolism in man and dog: mass spectrometric identification of six new metabolites J Pharmacol Exp Ther. 1972 Jul;182(1):83-92.

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