Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012070)
Formula
FMO5 ...
SVG example
Unclear
Reactant Deacetyl-esonarimod(M1) Product S-methyl-esonarimod(M2)
Reactant Info Product Info
Metabolic Enzyme Dimethylaniline oxidase 5 (FMO5) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012069 Esonarimod Deacetyl-esonarimod(M1) Unclear - Unclear Esonarimod [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012071 S-methyl-esonarimod(M2) 4-hydroxy-S-methyl-esonarimod Unclear - Unclear Esonarimod [2]
MR012072 S-methyl-esonarimod(M2) Sulfoxide-S-methyl-esonarimod Unclear - Unclear Esonarimod [2]
References
1 S-oxidation of S-methyl-esonarimod by flavin-containing monooxygenases in human liver microsomes
2 Identification of Hypoxia-inducible factor (HIF) stabilizer roxadustat and its possible metabolites in thoroughbred horses for doping control

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