Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012344)
Formula
CYP2C9 ...
SVG example
Unclear
Reactant HPPH Product Catechol
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012343 HPPH HPPH O-glucuronide Unclear - Unclear HPPH [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004300 Benzoic acid Catechol Unclear Naphthoquinone [2]
MR010926 Guaiacol Catechol Unclear - Unclear Isovanillin [3]
MR010925 Protocatechuic acid Catechol Unclear - Unclear Isovanillin [3]
MR013587 Pyrogallol Catechol Unclear Epigallocatechin gallate [4]
MR004867 5-methoxysalicylic acid Catechol Multi-steps Reaction - Demethylation; Reduction Naproxen [5]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004868 Catechol Cis-cis muconic acid Unclear Naproxen [5]
References
1 Role of CYP2C9, CYP2C19 and EPHX Polymorphism in the Pharmacokinetic of Phenytoin: A Study on Uruguayan Caucasian Subjects
2 Identification of naphthalene metabolism by white rot fungus Pleurotus eryngii
3 The metabolism of vanillin and isovanillin in the rat
4 Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
5 Utilization of naproxen by Amycolatopsis sp. Poz 14 and detection of the enzymes involved in the degradation metabolic pathway

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