Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012549)
Formula
SVG example
Unclear
Reactant TCN Product TCN-P
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012548 TCN-P TCN Unclear - Unclear TCN-P [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006147 PTX-200 Triciribine phosphate Unclear PTX-200 [4]
References
1 High-performance liquid chromatographic assay of the antineoplastic agent tricyclic nucleoside 5'-phosphate and its disposition in rabbit
2 Mechanism of activation of triciribine phosphate (TCN-P) as a prodrug form of TCN
3 Development and validation of LC/MS/MS method for Triciribine and its monophosphate metabolite in plasma and RBC: Application to mice pharmacokinetic studies
4 Phosphorylation of triciribine is necessary for activity against HIV type 1. AIDS Res Hum Retroviruses. 1998 Oct 10;14(15):1315-22.

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