Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012681)
Formula
SVG example
Hydroxylation
Reactant Irofulven metabolite 6 (M6) Product Irofulven metabolite 5 (M5)
Reactant Info Product Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012680 MGI-114 Irofulven metabolite 6 (M6) Unclear - Unclear MGI-114 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012678 Irofulven metabolite 4 (M4) Irofulven metabolite 5 (M5) Unclear - Unclear MGI-114 [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012679 Irofulven metabolite 5 (M5) M5-glucuronide conjugate (M'5) Conjugation - Glucuronidation MGI-114 [1]
References
1 Pharmacokinetics, metabolism, and routes of excretion of intravenous irofulven in patients with advanced solid tumors

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