Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012891)
Formula
SVG example
Reactant Mevalonate Product Isopentenyl 5-diphosphate
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012882 Mevalonate Mevalonate 3-phosphate Unclear Mevalonate [1]
MR002979 Mevalonate Cholesterol Unclear - Unclear Acetyl-CoA [2], [3], [4]
References
1 Evidence of a novel mevalonate pathway in archaea
2 Compartmentalised acyl-CoA metabolism and roles in chromatin regulation Mol Metab. 2020 Aug;38:100941. doi: 10.1016/j.molmet.2020.01.005.
3 Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis. Redox Biol. 2023 Jun 16;64:102771. doi: 10.1016/j.redox.2023.102771.
4 (2)H,(13)C-Cholesterol for Dynamics and Structural Studies of Biological Membranes. ACS Omega. 2022 May 10;7(20):17151-17160. doi: 10.1021/acsomega.2c00796.

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