Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013101)
Formula Reactant ABT-333 Metabolite M4 Product ABT-333 Metabolite M5
Reactant Info Product Info
Metabolic Enzyme DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013100 ABT-333 Metabolite M1 ABT-333 Metabolite M4 Oxidation - Oxidation ABT-333 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013102 ABT-333 Metabolite M5 ABT-333 Metabolite M6 Conjugation - Conjugation ABT-333 [1]
MR013104 ABT-333 Metabolite M5 ABT-333 Metabolite M8 Reduction - Reduction ABT-333 [1]
References
1 Metabolism and disposition of hepatitis C polymerase inhibitor dasabuvir in humans. Drug Metab Dispos. 2016 Aug;44(8):1139-47.

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