Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013127)
Formula	Hydroxylation
	Reactant	Trametinib	Product	Trametinib Metabolite M3
	Reactant	Reactant Info	Product	Product Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013125	Trametinib	Trametinib Metabolite M1	Oxidation - Deacetylation	Trametinib	[1]

References
1	Pharmacokinetic Interaction Between the MEK1/MEK2 Inhibitor Trametinib and Oral Contraceptives Containing Norethindrone and Ethinyl Estradiol in Female Patients With Solid Tumors

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