Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013141)
Formula Reactant MP Product DP
Reactant Info Product Info
Metabolic Type Conjugation - Di-phosphorylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013140 Ribavirin MP Conjugation - Mono-phosphorylation Ribavirin [1], [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013142 DP TP Conjugation - Triphosphorylation Ribavirin [1], [2]
References
1 Pharmacokinetics and metabolism of [(14)C]ribavirin in rats and cynomolgus monkeys
2 Sofosbuvir and Ribavirin Liver Pharmacokinetics in Patients Infected with Hepatitis C Virus
3 Adenosine kinase is a key determinant for the anti-HCV activity of ribavirin

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