Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013145)
Formula
SVG example
Demethylation
Reactant (Z)-endoxifen Product Norendoxifen
Reactant Info Product Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013143 (Z)-endoxifen Endoxifen O Glucuronide Unclear - Unclear (Z)-endoxifen [1]
MR013144 (Z)-endoxifen EndoxifenSulfate Unclear - Unclear (Z)-endoxifen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011557 Endoxifen Norendoxifen Oxidation - Demethylation Endoxifen [1]
MR003517 Endoxifen Norendoxifen Oxidation - Demethylation Tamoxifen citrate [2]
References
1 Clinical pharmacokinetics and pharmacogenetics of tamoxifen and endoxifen
2 PharmGKB:Tamoxifen citrate

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