Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013188)
Formula
SVG example
Reactant isonicotinyl-formamide Product Isonicotinic acid
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013187 Piroximone isonicotinyl-formamide Unclear Piroximone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001241 Isoniazid Isonicotinic acid Unclear Isoniazid [2]
MR009733 Motesanib Motesanib Mx Unclear - Unclear Motesanib [3]
MR001233 Acetylisoniazid Isonicotinic acid Unclear Isoniazid [2]
References
1 Metabolism and pharmacokinetics of the cardiotonic agent piroximone and of its major metabolite in dog
2 Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis J Pharm Biomed Anal. 2021 Sep 5;203:114223. doi: 10.1016/j.jpba.2021.114223.
3 In vitro metabolism of the novel, highly selective oral angiogenesis inhibitor motesanib diphosphate in preclinical species and in humans

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