Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013259)
Formula Reactant R-7-Hydroxywarfarin Product R-7-Hydroxywarfarin sulfate
Reactant Info Product Info
Metabolic Type Conjugation - Sulfation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013258 Warfarin sodium R-7-Hydroxywarfarin Oxidation - 7-hydroxylation Warfarin sodium [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013260 R-7-Hydroxywarfarin R-7-Hydroxywarfarin glucuronide metabolite Conjugation - Glucuronidation Warfarin sodium [1], [2]
References
1 Comparative pharmacokinetics of vitamin K antagonists: warfarin, phenprocoumon and acenocoumarol. Clin Pharmacokinet. 2005;44(12):1227-46.
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development Curr Med Chem. 2009;16(27):3480-675. doi: 10.2174/092986709789057635.

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