Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013262)
Formula Reactant R-4'-Hydroxywarfarin Product R-4'-Hydroxywarfarin glucuronide metabolite
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013261 Warfarin sodium R-4'-Hydroxywarfarin Oxidation - 4'-hydroxylation Warfarin sodium [1], [2]
References
1 Comparative pharmacokinetics of vitamin K antagonists: warfarin, phenprocoumon and acenocoumarol. Clin Pharmacokinet. 2005;44(12):1227-46.
2 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development Curr Med Chem. 2009;16(27):3480-675. doi: 10.2174/092986709789057635.

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