Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013295)
Formula
	Reactant	N-Desesethylzaleplon	Product	DDZAL
	Reactant	Reactant Info	Product	Product Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013293	Zaleplon	N-Desesethylzaleplon	Oxidation - N-dealkylation	Zaleplon	[1], [2], [3]

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013294	N-Desesethylzaleplon	N-desethyl-5-oxo-ZAL (M1)	Oxidation - Oxidationn	Zaleplon	[1], [2], [3]

References
1	Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene
2	Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase. Xenobiotica. 2002 Oct;32(10):835-47.
3	Separation and identification of zaleplon metabolites in human urine using capillary electrophoresis with laser-induced fluorescence detection and liquid chromatography-mass spectrometry

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