Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013605)
Formula Reactant Diacerein Product Rhein Metabolite M5
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013595 Diacerein Rhein Oxidation - Deacetylation Diacerein [1], [2]
MR013604 Diacerein Rhein Metabolite M28 Conjugation - Glucuronidation Diacerein [1]
References
1 Rapid characterization of the potential active metabolites of diacerein in rat plasma based on UHPLC-Q-exactive orbitrap mass spectrometry and molecular docking
2 Clinical pharmacokinetics of diacerein

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