Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR013788)
Formula	Glucuronidation
	Reactant	Berberrubine		Product	Berberrubine-9-O-beta-D-glucuronide
	Reactant	Reactant Info		Product	Product Info
Metabolic Type	Conjugation - Glucuronidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Produce The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013787	Berberine	Berberrubine	Oxidation - Demethylation	Berberine	[1], [2], [3]

References
1	The metabolism of berberine and its contribution to the pharmacological effects
2	CYP2D plays a major role in berberine metabolism in liver of mice and humans
3	Transformation of berberine to its demethylated metabolites by the CYP51 enzyme in the gut microbiota

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