General Information of This Metabolic Reaction (MR) (ID: MR014049)
Formula Reactant Hydroxyflutamide metabolite Flu-1 Product Hydroxyflutamide metabolite Flu-3
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005049 Flutamide Flutamide Metabolite M3 Unclear Flutamide [1]
MR007734 Hydroxyflutamide Hydroxyflutamide metabolite Flu-1 Unclear - Unclear Hydroxyflutamide [2]
MR007730 Hydroxyflutamide metabolite M1 Hydroxyflutamide metabolite Flu-1 Unclear - Unclear Hydroxyflutamide [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005052 Flutamide Metabolite M3 Flutamide Metabolite M4 Unclear Flutamide [1]
MR005050 Flutamide Metabolite M3 Flutamide Metabolite M5 Unclear Flutamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014050 Hydroxyflutamide metabolite Flu-3 Hydroxyflutamide metabolite Flu-3 glucuronide Unclear - Unclear Hydroxyflutamide [2]
MR007733 Hydroxyflutamide metabolite Flu-3 Hydroxyflutamide metabolite Flu-3 sulphate Unclear - Unclear Hydroxyflutamide [2]
References
1 Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites
2 Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry

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