Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR014152)
Formula
SVG example
Amid hydrolysis
Reactant Ombitasvir Product Ombitasvir Metabolite M7
Reactant Info Product Info
Metabolic Type Hydrolysis - Amid hydrolysis
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR014142 Ombitasvir Ombitasvir Metabolite M23 Hydrolysis - Amid hydrolysis Ombitasvir [1]
MR014169 Ombitasvir Ombitasvir Metabolite M3 Other reaction - Hydration Ombitasvir [1]
MR014154 Ombitasvir Ombitasvir Metabolite M5 Oxidation - Hydroxylation Ombitasvir [1]
MR014151 Ombitasvir Ombitasvir Metabolite M6 Hydrolysis - Amid hydrolysis Ombitasvir [1]
MR014153 Ombitasvir Ombitasvir Metabolite M9 Hydrolysis - Amid hydrolysis Ombitasvir [1]
References
1 Metabolism and disposition of pan-genotypic inhibitor of hepatitis C virus NS5A ombitasvir in humans. Drug Metab Dispos. 2016 Aug;44(8):1148-57.

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