Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00005)
Xenobiotics Name
Theophylline
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
2153
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Amiloride-sensitive amine oxidase (AOC1) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME Info Homo sapiens [2], [3]
DME(s) Induced by This Xenobiotics
Thiopurine methyltransferase (TPMT) DME Info Homo sapiens [4]
References
1 Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells. Mutagenesis. 2011 Sep;26(5):593-604.
2 Dioxin exposure of human CD34+ hemopoietic cells induces gene expression modulation that recapitulates its in vivo clinical and biological effects. Toxicology. 2011 Apr 28;283(1):18-23.
3 Gene expression changes in human small airway epithelial cells exposed to Delta9-tetrahydrocannabinol. Toxicol Lett. 2005 Aug 14;158(2):95-107.
4 The transcriptional signature of dioxin in human hepatoma HepG2 cells. Biochem Pharmacol. 2000 Oct 15;60(8):1129-42.

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