Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00025)
Xenobiotics Name
Dichlorphenamide
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
3038
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Carbonic anhydrase II (CA2) DME Info Homo sapiens [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Carbonic anhydrase II (CA2) DME Info IC50 = 0.038 microM [1], [2]
References
1 Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition. J Med Chem. 2004 Jan 29;47(3):550-7.
2 Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. Bioorg Med Chem Lett. 2004 Jan 19;14(2):337-41.

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