Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00063)
Xenobiotics Name
Metyrapone
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
4174
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) DME Info Homo sapiens [1]
Estradiol 17-beta-dehydrogenase 1 (HSD17B1) DME Info Homo sapiens [2], [3]
References
1 Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. Cancer Res. 2003 Jan 1;63(1):52-9.
2 Microarray data mining for potential selenium targets in chemoprevention of prostate cancer. Cancer Genomics Proteomics. 2005 Apr;2(2):97-114.
3 Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers. Mol Cancer Ther. 2005 Jul;4(7):1047-55.

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