General Information of Xenobiotics (ID: XEO00089)
Xenobiotics Name
Mitomycin
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
5746
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Thymidine phosphorylase (TYMP) DME Info Homo sapiens [1]
Uridine 5'-monophosphate synthase (UMPS) DME Info Homo sapiens [2]
Xanthine dehydrogenase/oxidase (XDH) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [3]
Thymidylate synthase (TYMS) DME Info Homo sapiens [2]
References
1 Identification of temporal differentially expressed protein responses to microcystin in human amniotic epithelial cells. Chem Res Toxicol. 2009 Jan;22(1):41-51.
2 Mifepristone induced progesterone withdrawal reveals novel regulatory pathways in human endometrium. Mol Hum Reprod. 2007 Sep;13(9):641-54.
3 Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug Metab Dispos. 2006 Oct;34(10):1742-8.

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